Cystitis is the term used to describe inflammation of the bladder mucosa.
Cystitis andother urinary tract infections
Cystitis is characterised by a frequent urge to urinate and pain when urinating. You can find the most important facts regarding cystitis and similar illnesses here.
What will be discussed
What is cystitis?
Cystitis refers to the inflammation of the bladder mucosa, and sometimes the entire bladder wall. The urethra is usually also affected. Inflammation occurs when bacteria ascend into the bladder via the urethra and multiply. It is usually caused by bacteria (e.g. Escherischia coli), but fungi, viruses or parasites can also cause cystitis in rare cases.
This results in:
- frequent, strong urge to urinate
- pain or a burning sensation when urinating and/or in the bladder
- only being able to pass a small amount of urine when going to the toilet
Different types of cystitis
Cystitis can be divided into two categories: acute, i.e. recent onset, or chronic. Chronic cystitis is the term used when at least two or three infections have occurred within six months of each other.
Doctors also differentiate between an uncomplicated and a complicated urinary tract infection. This is a very important distinction, as a complicated urinary tract infection comes with a higher risk of complications. Risk factors include pre-existing conditions such as kidney stones, poorly controlled or uncontrolled diabetes or an immunodeficiency. A complicated urinary tract infection may also occur if your urinary tract is malformed, you have kidney failure or are pregnant.
The body relies on constantly excreting metabolic products and harmful substances via the kidneys and bladder. It also regulates the amount of fluid in the body. A dysfunction of these organs puts a strain on the entire body in the long term. It is therefore important for your doctor to assess whether the urinary tract infection is uncomplicated or whether other illnesses or circumstances need to be included in the assessment.
Inflammation of the renal pelvis: the result of ascending bacteria
If left untreated, cystitis can develop into an unpleasant inflammation of the renal pelvis, known as pyelitis. The bacteria travel up through the ureters and then infect the kidneys. As a result, many patients suffer from weakness, fever, back pain or even nausea and vomiting. It is essential to consult your doctor, as you will need antibiotics.
How is a urinary tract infection diagnosed?
Do you have the typical symptoms of a strong urge to urinate, frequent urination and a burning sensation in the urethra or pain in the bladder or lower abdomen? Always seek medical advice. A urine analysis may also be carried out alongside a physical examination.
It is important to diagnose cystitis promptly and correctly and to treat it appropriately! Otherwise, chronic inflammation of the urinary bladder or, in rare cases, inflammation of the renal pelvis may occur.
It is important to diagnose cystitis promptly and correctly and to treat it appropriately! Otherwise, chronic inflammation of the urinary bladder or, in rare cases, inflammation of the renal pelvis may occur. Should this be the case, further examinations, e.g. ultrasound will be carried out. A urine culture will also be taken in the event of pyelitis. This involves cultivating bacteria contained in the urine on a culture medium, which will allow your doctor to determine which treatment will work best.
Uncomplicated cystitis will heal on its own in 30–50% of cases. So, you can keep unpleasant side effects at bay with a few measures to support the bladder, mild painkillers and heat. If the right antibiotic is prescribed at the same time, the symptoms will subside more quickly, and the bacteria causing them can be killed off effectively. However, antibiotics can also cause more side effects and promote the resistance of bacteria to these drugs. This is why it makes sense to test which antibiotic works well against the causative bacteria in the laboratory. You should consult your doctor about whether painkillers are sufficient or whether you need antibiotics.
If the infection has already progressed into pyelitis, it should be treated as early as possible with an appropriate antibiotic. The longer and more severely the kidney is infected, the more damage the organ can suffer.
Causes of cystitis
Various factors increase the risk of contracting a urinary tract infection.
Make sure you drink enough, particularly water. This ensures that the bladder is flushed out regularly and no bacteria can accumulate in it.
Always wipe from front to back after using the toilet, never the other way round. Otherwise, bacteria from the intestines can enter the vagina and urethra.
The pH of the vagina changes due to hormonal fluctuations, allowing germs from the intestine to colonise the skin or mucous membrane of the vagina and bladder. KadeFlora Lactic Acid Treatment (KadeFlora Milchsäurekur) stabilises the pH and reduces the risk of recurring urinary tract infections.
During unprotected sex or when switching from anal to vaginal intercourse, foreign microbes can enter the vagina and travel to the urinary tract. Using a diaphragm or spermicide as contraception can also increase the risk of developing cystitis.
If urine cannot drain properly due to bladder stones, urine residue forms. A small amount of fluid is left in the bladder, in which bacteria can thrive.
If you are under a lot of stress or your immune system is compromised, it may not be able to defend itself against germs that enter the body.
Things like damp swimwear, cold stone slabs, etc. aren’t good for your bladder, as they cause the mucous membranes to be less well supplied with blood, which reduces their ability to defend themselves.
The risk of urinary tract infections also increases if you have already had cystitis or if other members of your family are also prone to it. If you had your first urinary tract infection before the age of 15, you are also more likely to suffer from it again later in life.
How to prevent cystitis
There are ways to effectively prevent cystitis. These tips can also make life a little easier if you have previously suffered from cystitis or chronic bladder complaints.
Flush out the bladder
To prevent cystitis, you should drink plenty of fluids, especially water, herbal tea or diluted fruit juices. Make sure to go to the toilet in plenty of time, and not just when you are desperate. Make sure to always empty your bladder fully. This will help you to keep your bladder well flushed and ensure the bacteria cannot survive.
If you hold in your urine for a long time or do not empty your bladder completely, you may develop what is known as residual urine, where a small amount of fluid always remains in the bladder. This is the perfect environment for pathogens to multiply undisturbed, resulting in cystitis.
Intimate hygiene – as much as necessary, as little as possible
You don’t need harsh shower gels or intimate deodorants to maintain intimate hygiene. Warm water and perhaps a mild intimate wash lotion with an optimal pH are perfectly adequate. This prevents irritation and weakening of the healthy bacterial flora on the skin and mucous membranes and prevents cystitis.
Always wipe from front to back after using the toilet. Otherwise, intestinal bacteria can enter the vagina and urethra and cause problems.
Underwear should preferably be made of cotton and washed at a temperature of at least 60°C, as this will kill all bacteria and prevent bladder infections. (There are also sanitisers that achieve this at lower temperatures). In addition, cotton underwear causes less heat build-up when cycling or in hotter climates, which in turn protects delicate intimate skin.
Note: One study suggests that vaginal infections with the bacterium Gardnerella vaginalis can lead to cystitis1.
Lactic acid treatments such as the KadeFlora Lactic Acid Treatment (KadeFlora Milchsäurekur) can be used to effectively prevent cystitis: KadeFlora Lactic Acid Treatment (KadeFlora Milchsäurekur) lowers the pH of the vagina so that pathogens can no longer multiply, while the vaginal flora is strengthened.
Sex and cystitis
During unprotected sexual intercourse, bacteria from the intestines can be introduced into the vagina, which can then find their way into the urinary bladder as you move. Condoms offer a certain degree of protection. Spermicides or a diaphragm can disrupt the sensitive vaginal flora and are therefore rather ineffective at preventing cystitis.
Note: Doctors often refer to ‘honeymoon’ cystitis or ‘honeymoon sickness’ as many women get cystitis from having sex during their honeymoon.
‘Honeymoon cystitis’ is a normal inflammation of the bladder, the name of which refers to the cause.
But you don’t have to have been on your honeymoon to get cystitis from sex. You can prevent this by going to the toilet soon after intercourse. Any unwanted bacteria are flushed out immediately and prevents cystitis. You can also support your vaginal flora after intercourse by using lactic acid to restore the acidic vaginal pH (e.g. KadeFlora Lactic Acid Treatment (KadeFlora Milchsäurekur)).
You can prevent cystitis by avoiding exposure to cold: It is best to take off your wet swimwear straight after swimming, not expose your feet to cold temperatures and to not sit on cold stone slabs, as this weakens local defences and makes it easier for bacteria to colonise the bladder.
Note: Even crop tops can make it easier to develop cystitis or a kidney infection.Â
A balanced diet, plenty of sleep and sufficient exercise generally help to maintain good health. Cystitis is no match for a strong immune system!
Cranberry juice has been used in North American natural medicine for a very long time to prevent cystitis. However, it has not yet been conclusively proven that cranberry juice or cranberry products have a quantifiable effect.
Lower oestrogen levels in the blood during and after the menopause alter the vaginal flora. The thickness of the mucous membrane and its population of lactic acid bacteria (lactobacilli) decrease, while the vaginal pH increases. This reduces the vagina’s ability to fight off pathogens, allowing them to enter the urethra and cause a bladder infection.
Many menopausal women therefore benefit from medication containing oestrogen for frequently recurring cystitis: This regulates the hormonal imbalance and prevents bladder inflammation.
Any underlying illness that weakens your defences must also be treated accordingly, as this reduces the overall risk of infections, including cystitis.
Immunostimulation can also be used to prevent or treat chronic cystitis: Similar to a vaccination, the immune system is stimulated to fight the pathogens more effectively. The strength of the effect is still being debated in the scientific community.
Zur Vorbeugung oder Behandlung bei chronischer Blasenentzündung gibt es auch die Möglichkeit einer Immunstimulation: Ähnlich einer Impfung wird das Immunsystem animiert, die Krankheitserreger vermehrt zu bekämpfen. Über die Stärke der Wirkung wird in der Wissenschaft derzeit noch diskutiert.
1Gilbert, N. M., O’Brien, V. P., Lewis, A. L., Wang, A., & Amaral, F. (2017). Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease. PLOS Pathogens, 13(3), e1006238. https://doi.org/10.1371/journal.ppat.1006238